Weekly Dose of Optimism #195
Eli Lilly has developed a promising gene therapy targeting LDL cholesterol, potentially preventing heart disease with a single infusion. The therapy has shown significant reductions in LDL cholesterol levels during early trials. This breakthrough could significantly impact global health, as high LDL cholesterol is linked to millions of deaths annually.
- ▪Eli Lilly's gene therapy targets PCSK9, responsible for LDL cholesterol, showing reductions of up to 62%.
- ▪High LDL cholesterol contributes to approximately 4.4 million deaths each year worldwide.
- ▪The therapy could provide long-term benefits with a single treatment, unlike current PCSK9 medications that require ongoing use.
Opening excerpt (first ~120 words) tap to expand
Weekly Dose of Optimism #195LDL Gene Therapy, GLP-1s slow Cancer, Supersonic Hermeus, Nanotech, Moon Base + Extra DosesMay 29, 2026∙ PaidShareHi friends 👋, Happy Friday, and welcome to our 195th Weekly Dose of Optimism.Man, just when I thought it was going to be hard to top last week’s Dose, we have an LDL cholesterol-fighting gene therapy, evidence that GLP-1s slow cancer, supersonic flight, and nanotech, and a Moon Base. We also have the coolest Science Breakthroughs roundup yet. Even a massive Blue Origin explosion can’t slow us down. If you get through this and want even more optimism injected into your veins, check out this week’s essay: Let’s get to it.
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Excerpt limited to ~120 words for fair-use compliance. The full article is at Not Boring.
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