Weekly Dose of Optimism #194
Eli Lilly's Phase 3 trial for retatrutide has shown remarkable results in weight loss for adults with obesity. Participants lost an average of 28.3% of their body weight over 80 weeks, with significant improvements in various health markers. Additionally, Colossal Biosciences has successfully hatched chicks from fully artificial eggs, marking a significant milestone in biotechnology.
- ▪Eli Lilly reported that participants in the retatrutide trial lost an average of 28.3% of their body weight over 80 weeks.
- ▪The trial also showed significant drops in blood pressure, triglycerides, and waist circumference.
- ▪Colossal Biosciences announced the hatching of 26 healthy chicks from fully artificial eggs.
Opening excerpt (first ~120 words) tap to expand
Weekly Dose of Optimism #194Reta Phase 3, Colossal Eggs, SpaceX, OpenAI x Erdős, SendCutSend + Extra DosesMay 22, 2026∙ PaidShareHi friends 👋,Happy Friday and welcome to our 194th Weekly Dose of Optimism. I’m emailing you from beautiful Utah, where I attended the Abundance Institute Gala last night and got to talk nuclear with Oklo’s Jake DeWitte and General Matter’s Scott Nolan, and where I’ll be spending today at the state’s Operation Gigawatt Conference. It’s hard not to feel the optimism in the mountain air. When we started writing the Dose a few years back, nuclear was a controversial dream. Today, we’re heading into the Memorial Day Weekend that kicks off the summer during which multiple new reactors will go critical for the first time.
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Excerpt limited to ~120 words for fair-use compliance. The full article is at Not Boring.