Trial Questions Extended Antibiotics After Bladder Removal
A recent trial suggests that extended antibiotics may not be necessary after cystectomy, as interim results show no increased risk of urinary tract infections (UTIs). The study found similar UTI rates in patients who received prophylaxis and those who did not. These findings could lead to more standardized antibiotic use in post-operative care for bladder cancer patients.
- ▪The trial indicated that the rate of UTIs was 12% in both groups, regardless of antibiotic prophylaxis.
- ▪The study aims to establish evidence-based guidelines for antibiotic use after cystectomy, addressing a common clinical issue.
- ▪Initial results showed lower overall readmissions and complications without extended prophylaxis.
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Omitting extended antibiotics after cystectomy does not appear to increase the risk for urinary tract infection (UTI) associated with the procedure, according to interim results from a small, randomized trial.The rate of UTIs after removal of ureteral stents was 12% in both patients who received prophylaxis and those who did not (2 out of 16-17 patients in each arm) in the first 30 days and the subsequent 60 days after the procedure.The study could help bring some consistency to antibiotic stewardship in patients who undergo cystectomy, of whom roughly 1 in 8 develop a UTI.
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Excerpt limited to ~120 words for fair-use compliance. The full article is at Medscape.
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