Telephone Weight-Loss Coaching Pays Off in Breast Cancer
A telephone-based weight-loss coaching program has shown positive effects on women with early breast cancer. Participants reported improvements in physical and mental health, as well as social functioning, after six months of coaching. These benefits persisted for two years, although the overall gains were modest and did not significantly impact anxiety or depression levels.
- ▪Women in the coaching program reported better physical function, mental health, and social functioning compared to control individuals.
- ▪The intervention resulted in a 1.9-point improvement in physical function and a 2.3-point improvement in social functioning after six months.
- ▪The study involved over 3000 women with stage II/III HER2-negative breast cancer and a BMI of at least 27.
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A weight-loss program delivered mostly over the phone improved physical function, social function, and mental health in women with overweight or obesity and early breast cancer, according to a substudy of a phase 3 trial.At 6 months, women who received coaching reported better outcomes than control individuals across multiple measures, including physical function, physical health, mental health, and social functioning, while also reporting less fatigue. Improvements in all domains except fatigue persisted at 2 years.The telephone-based weight-loss intervention “was successful in inducing durable improvements,” said lead investigator Jennifer Ligibel, MD, while presenting the findings at a preconference press briefing for the American Society of Clinical Oncology (ASCO) 2026.The findings…
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