Supercharging Immune Cells May Help Control HIV Long-Term
A small study suggests that CAR-T cell therapy, typically used for cancer treatment, may help control HIV long-term. Two individuals in the trial achieved undetectable levels of the virus after receiving modified immune cells, allowing them to stop HIV medications. Researchers are optimistic about the potential for this approach to be optimized for broader use in HIV treatment.
- ▪CAR-T cell therapy has shown early promise in managing HIV in a small clinical trial.
- ▪Two participants achieved undetectable levels of the virus after a single infusion of modified immune cells.
- ▪The study was presented at the American Society of Gene and Cell Therapy annual meeting in Boston.
Opening excerpt (first ~120 words) tap to expand
Emily MullinScienceMay 18, 2026 6:30 AMSupercharging Immune Cells May Help Control HIV Long-TermCAR-T cell therapy is already a potent treatment for certain cancers. Now, a small study is showing early promise for managing HIV.Photograph: Bloomberg/Getty ImagesCommentLoaderSave StorySave this storyCommentLoaderSave StorySave this storyA Miracle cancer therapy that involves engineering a patient’s own immune cells is being repurposed for HIV, and early results from two individuals hint at its promise for long-term control of the virus.As part of a clinical trial, scientists took people’s own immune cells and reprogrammed them in a lab to recognize and attack HIV in the body.
…
Excerpt limited to ~120 words for fair-use compliance. The full article is at WIRED.