People lost up to 85 pounds on Lilly’s experimental weight loss drug, company says
Eli Lilly's experimental weight loss drug, retatrutide, has shown promising results in a late-stage clinical trial, with participants losing up to 85 pounds. The weight loss achieved is comparable to that of bariatric surgery, marking a significant milestone in medication trials. The company plans to seek FDA approval for the drug later this year.
- ▪Retatrutide helped participants lose up to 30% of their body weight, averaging 85 pounds.
- ▪The trial involved about 2,300 patients with obesity or who are overweight and lasted for 80 weeks.
- ▪Side effects included nausea, constipation, and diarrhea, common with GLP-1 drugs.
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Health newsPeople lost up to 85 pounds on Lilly’s experimental weight loss drug, company saysThe results — the most weight loss ever seen in a medication trial — put the drug’s effectiveness on par with bariatric surgery. Listen to this article with a free account00:0000:00Eli Lilly headquarters in Indianapolis. AJ Mast / Bloomberg via Getty Images file ShareAdd NBC News to GoogleMay 21, 2026, 6:45 AM EDTBy Berkeley Lovelace Jr.Eli Lilly’s highly anticipated new weight loss drug, retatrutide, helped people lose up to 30% of their body weight, about 85 pounds, in a late-stage clinical trial, the drugmaker said in a news release Thursday.Subscribe to read this story ad-free Get unlimited access to ad-free articles and exclusive content.The results are on par with bariatric surgery, which…
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