Maternal Overnutrition Linked to Obesity in Adult Offspring
A systematic review has found that maternal overnutrition is linked to higher rates of obesity in adult offspring. The study indicates that this association remains significant into adulthood, particularly affecting women more than men. Researchers emphasize the importance of managing maternal weight before and during pregnancy to mitigate long-term obesity risks in children.
- ▪Maternal overnutrition was associated with increased odds of obesity in offspring, persisting into adulthood.
- ▪Offspring of mothers with obesity had 4.04-fold higher odds of obesity compared to those of normal-weight mothers.
- ▪Excessive gestational weight gain was linked to a 35% higher risk of obesity in adult offspring.
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TOPLINE:Maternal overnutrition was associated with increased odds of obesity in offspring; this association persisted into adulthood and did not diminish after the age of 30 years, with more pronounced effects observed in women than in men.METHODOLOGY:Researchers conducted a systematic review and meta-analysis to evaluate the effect of maternal overnutrition on overweight or obesity in adult offspring and to assess whether this association persisted into adulthood and differed by offspring age and sex.A total of 29 English language studies, predominantly prospective cohort studies (n = 22), comprising 430,764 mother-offspring pairs published between 2001 and 2024 were included after a literature search across various databases.
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Excerpt limited to ~120 words for fair-use compliance. The full article is at Medscape.
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