Maternal Diabetes in Pregnancy Tied to CVD Risk in Children
A study has found that children whose mothers had diabetes during pregnancy face a higher long-term risk of cardiovascular disease (CVD). The risk is particularly elevated when diabetes was present before pregnancy. Congenital heart defects and adverse birth outcomes contribute significantly to this association.
- ▪Individuals whose mothers had diabetes during pregnancy had an increased long-term risk for cardiovascular disease.
- ▪Any maternal diabetes was associated with a 16% increased risk for overall CVD in offspring.
- ▪Congenital heart disease and preterm birth explained a significant portion of the overall association.
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TOPLINE:Individuals whose mothers had diabetes during pregnancy had an increased long-term risk for cardiovascular disease (CVD), especially when diabetes was present before pregnancy. Part of this association was explained by congenital heart defects, preterm birth, and large size at birth in offspring.METHODOLOGY:Researchers conducted a population-based cohort study to examine the association between maternal diabetes during pregnancy and later risk for CVD in offspring and related factors.They used linked Swedish registers and included over 4.2 million singleton births between January 1973 and December 2014; the mean age at the end of follow-up was 27.4 years, and 51.39% were men.Offspring were categorized based on whether their mothers had diabetes during pregnancy.
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