'Longevity gene' may protect the brain from Alzheimer's by boosting DNA repair, study finds
A recent study has identified the APOE2 gene as a potential protector against Alzheimer's disease by enhancing DNA repair in brain cells. Researchers found that this gene helps neurons resist aging and dysfunction, contrasting with the more harmful APOE4 variant. These findings suggest that the APOE2 gene may contribute to longevity and lower Alzheimer's risk.
- ▪The APOE2 gene improves neurons' ability to repair DNA damage and resist cellular senescence.
- ▪Brain cells with the APOE4 variant are more fragile and show signs of aging and dysfunction.
- ▪The study was conducted using human brain cells derived from stem cells and supported by follow-up studies in mice.
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Health 'Longevity gene' may protect the brain from Alzheimer's by boosting DNA repair, study finds Researchers find APOE2 gene helps neurons repair DNA damage and resist cellular senescence By Melissa Rudy Fox News Published May 19, 2026 7:00am EDT Facebook Twitter Threads Flipboard Comments Print Email Add Fox News on Google close Video Alzheimer’s could be reversed by restoring brain balance, study suggests Fox News senior medical analyst Dr. Marc Siegel comments on a breakthrough study on Alzheimer’s disease performed on mice and what it means for humans on 'America Reports.' NEWYou can now listen to Fox News articles! A new study suggests that a specific "longevity gene" may help protect the brain from the effects of aging, including Alzheimer’s disease.
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