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Isotretinoin Plus Laser Safe, Effective for Rhinophyma

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Isotretinoin Plus Laser Safe, Effective for Rhinophyma
⚡ TL;DR · AI summary

A recent study indicates that combining CO2 laser resurfacing with isotretinoin is a safe and effective treatment for rhinophyma in rosacea patients. The study involved 15 adults and showed significant post-treatment improvements without complications. Patient satisfaction was high, with most reporting improvements in quality of life and no recurrence of the condition.

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Medscape
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SAVANNAH, Ga. — Combining carbon dioxide (CO2) laser resurfacing with isotretinoin is both safe and effective for treating rhinophyma in patients with rosacea, a new study suggests.Rhinophyma is a severe, advanced form of rosacea marked by the enlargement of sebaceous glands within the nasal tissue, making the nose appear bumpy, red, and bulbous.In a retrospective review of 15 adults with the condition, fully ablative CO2 laser therapy plus low-dose perioperative oral isotretinoin was associated with posttreatment improvement on photographic assessments by blinded reviewers, no delayed re-epithelialization or abnormal scarring, low recurrence, and high patient satisfaction.Study investigator Isabella Camacho-Hubbard, MD, Dermatology Laser & Vein Specialists of the Carolinas, Charlotte,…

Excerpt limited to ~120 words for fair-use compliance. The full article is at Medscape.

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