Femoral BMD May Reflect Broader Health in Older Women
New research indicates that femoral bone mineral density (BMD) may serve as a prognostic biomarker for overall health in older women. The study found that women with osteoporosis had a significantly increased risk of all-cause mortality, independent of other demographic and clinical factors. These findings emphasize the importance of assessing broader health metrics in this population.
- ▪Women with osteoporosis based on femoral BMD measurements had a 47% increased risk for all-cause mortality.
- ▪The study included nearly 3000 postmenopausal women and followed them for an average of 7.26 years.
- ▪BMD was found to be a better predictor of mortality than BMI, highlighting its potential as a marker for systemic health.
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Osteoporosis is a known risk factor for fractures, but new research published in Menopause suggested it may also provide insight into broader health outcomes.In an observational study, women who met criteria for osteoporosis based on femoral bone mineral density (BMD) measurements had a 47% increased risk for all-cause mortality after adjustment for demographic and clinical factors (hazard ratio [HR], 1.47; 95% CI, 1.16-1.86). Researchers also found that low BMD across four femoral regions — total femur, femoral neck, trochanter, and intertrochanteric — were associated with mortality risk.The association was strongest in total femur BMD ranges of 0.46-0.71 g/cm2 and trochanter BMD ranges of 0.33-0.54 g/cm2.“The study reveals a significant inverse correlation between femoral BMD and…
Excerpt limited to ~120 words for fair-use compliance. The full article is at Medscape.