Billions of doses later: Global review confirms mRNA vaccines safe and effective
A global review of mRNA vaccines has found them to be safe and highly effective in preventing infectious diseases. The review, which spans the full vaccine lifecycle, draws on laboratory science, clinical trials, and real-world effectiveness data. The findings confirm that mRNA vaccines provide strong protection against severe illness, hospitalization, and death, and have potential applications for a range of other diseases.
- ▪mRNA vaccines have been administered billions of times worldwide and have been found to be safe and highly effective.
- ▪The vaccines provide strong protection against infectious diseases, including severe COVID-19, across a wide range of groups.
- ▪Booster doses extend and strengthen protection over time, and regular updates to the vaccine formulation maintain efficacy as new variants emerge.
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A sweeping global review led by researchers at the University of British Columbia has found that mRNA vaccines—now administered billions of times worldwide—are safe and highly effective at preventing infectious diseases like COVID-19, and have potential applications for a range of other diseases, including influenza, RSV, cancer and autoimmune disorders. Published today in The Lancet, the review draws on laboratory science, clinical trials and real-world effectiveness data to provide one of the most comprehensive assessments of mRNA vaccines to date. It spans the full vaccine lifecycle, from design and manufacturing to real-world performance and monitoring.
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