2 subtle signs of Alzheimer’s may appear as early as age 45
A recent study suggests that subtle signs of Alzheimer's disease may appear as early as age 45. Researchers found that the accumulation of a toxic protein known as pTau181, along with self-reported memory issues, could indicate an increased risk of developing the disease. Early detection of these signs could lead to better treatment options and preventive measures.
- ▪Alzheimer's disease primarily affects individuals over 65, but signs may emerge two decades earlier.
- ▪The study involved over 1,000 participants, with an average age of 45 at the time of assessment.
- ▪Identifying early symptoms could improve treatment outcomes and allow for lifestyle changes to promote brain health.
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Health 2 subtle signs of Alzheimer’s may appear as early as age 45 By Rachel Sacks Published May 24, 2026, 12:20 p.m. ET See more of our coverage in your search results. Add The New York Post on Google Clues to a degenerative disease could be showing up sooner than we realize. Alzheimer’s disease primarily affects people over the age of 65, but a couple of subtle signs could come up to two decades before. And both could provide insight into how and when the disease develops over our lifetimes. While many aren’t diagnosed with Alzheimer’s disease until 65, two subtle signs could show up decades earlier. New Africa – stock.adobe.com The neurodegenerative disease that affects 6.7 million Americans potentially begins long before cognitive skills, attention span and judgement start eroding.
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