1,700 new protein found in the "dark proteome" of previously overlooked DNA
A recent study has identified 1,700 new proteins in the so-called 'dark proteome' of human DNA, expanding our understanding of the human proteome. These proteins, which were previously overlooked, may play significant roles in various biological processes. The findings could have implications for medical research and the development of new therapies.
- ▪The study discovered 1,700 new proteins in the human 'dark proteome'.
- ▪These proteins were previously unrecognized and may influence biological functions.
- ▪The research could lead to advancements in medical therapies and understanding of human biology.
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Nature Actions Search in PubMed Search in NLM Catalog Add to Search . 2026 May 6. doi: 10.1038/s41586-026-10459-x. Online ahead of print. Expanding the human proteome with microproteins and peptideins Eric W Deutsch # 1 , Leron W Kok # 2 3 , Jonathan M Mudge # 4 , Cristian F Valls # 5 6 , Irwin Jungreis # 7 8 , Jorge Ruiz-Orera 9 , Zhi Sun 1 , Ulrike Kusebauch 1 , Ivo Fierro-Monti 4 10 , Jennifer G Abelin 8 , M Mar Alba 11 12 , Julie L Aspden 13 , Sreejan Bandyopadhyay 14 , Kaushik Banerjee 5 6 , Pavel V Baranov 15 , Ariel A Bazzini 16 17 , Francis Bourassa 18 , Elspeth A Bruford 19 , Lorenzo Calviello 20 , Steven A Carr 8 , Anne-Ruxandra Carvunis 21 22 23 , Sonia Chothani 24 25 , Jim Clauwaert 5 , Kellie Dean 15 , Pouya Faridi 26 27 , Adam Frankish 4 , Amy Goodale 8 , Thomas Green 8 ,…
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